True.

Enzyme substrate binding occurs at the active site.

False.

The binding of substrate to enzyme often causes induced fit, a conformational change in enzyme and substrate.

True.

A change of pH to a pH above or below an enzyme's optimum pH may damage (or change) enzyme structure.
This will slow the rate of reaction.  If the pH change is very large the enzyme may be denatured.

True.

Molecules with a higher temperature have more energy, and move faster so colliding with each other more often.

True (usually)

When temperatures are high the hydrogen bonds holding the secondary structure of proteins are broken. 
This changes their shape and can denature the enzyme.
However, some enzymes e.g. Taq Polymerase, are tolerant of high temperature and will still function at 70°C.
Also: 30°C increase may not be enough to denature an enzyme if the starting temperature is below 15°C.

Note: This question is trying to get beyond the simple answer that too much heat energy will denature enzymes.

False.

A metabolic pathway has a sequence of reactions each controlled by a different enzyme specific for that reaction.

Note: Some metabolic pathways are controlled by end product inhibition (that's good thinking) but the statement is still false.  In these cases the inhibition of one enzyme restricts the whole pathway, but you wouldn't say that the enzyme is controlling the pathway, it's really the concentration of end product that controls it.

False.

Macromolecules are formed from monomers in condensation reactions.

True.

Many enzymes of metabolic pathways are membrane proteins, immobilised within the phospholipid bilayer.
(Immobilisation is also used in industry).

True.

Larger molecules (glucose, Triose phosphate TP, starch) are formed from smaller molecules (water, carbon dioxide).

True.

The substrate is converted into a product and so the concentration of substrate is reduced..